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View Article  Crafting Smaller, Faster Technologies
The decreasing size and increasing speed of analytic and other tools are helping researchers work more efficiently and productively.

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Drug Discovery and Development
View Article  Modeling Success in PK/PD Testing
A few years ago, there were many failures in phase III trials due to suboptimal dosing. PK/PD modeling tools are helping change that.

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Drug Discovery and Development
View Article  Generic Threats Loom For King Pharmaceuticals
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forbes.com
View Article  Health Affairs Sunday Health Policy Update - February 12, 2006
 

Sunday Health Policy UpDate
February 12, 2006
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New postings and analysis from Health Affairs, the leading journal of health policy. Health Affairspublishes new research each week online at www.healthaffairs.org. For more information, contact Chris Fleming at 301-347-3944.

Spending Increases Not Responsible for Improved Heart Attack Outcomes
http://content.healthaffairs.org/cgi/content/abstract/hlthaff.25.w34

In an article published Feb. 7 on the Health Affairs Web site, Dartmouth researchers Jonathan Skinner, Douglas Staiger, and Elliott Fisher challenge the conventional wisdom that growing health care costs are paying for new treatments and reduced mortality. The Dartmouth trio found that the factors fueling improvement in outcomes for heart attack patients from 1986 through 2002 were not the factors that fueled increases in costs, and much of the improvement occurred in U.S. regions exhibiting below-average growth in spending.

You can also read perspectives on the Dartmouth study by David Cutler and Alan Garber.http://content.healthaffairs.org/cgi/content/abstract/hlthaff.25.w48
http://content.healthaffairs.org/cgi/content/abstract/hlthaff.25.w51


For Surgeries, Physician-Owned Cardiac Hospitals Affect Where, Not Who
http://content.healthaffairs.org/cgi/content/abstract/25/1/119

Physician-owned cardiac specialty hospitals take market share from community hospitals, but they don’t appreciably increase the overall number of, or severity mix among, people receiving cardiac surgery, say Jeffrey Stensland and Ariel Winter in the January/February Health Affairs. This could be because surgery is less discretionary than services such as imaging studies and laboratory tests, where physician ownership does increase usage. Or, the researchers warn, it could be because the arms race between cardiac and community hospitals has only just begun.


Changing Physician Payment Incentives Entails Complex Trade-Offs
http://content.healthaffairs.org/cgi/content/abstract/25/1/219

In a report from the field in the January/February Health Affairs, Nora Super reminds us how pervasively financial incentives can affect physician behavior and how hard it is to say what the "right" incentives are. As Cincinnati Group Health Associates has moved from capitation to fee-for-service payment, GHA physicians have grown more willing to schedule unnecessary office visits and order unnecessary tests. On the other hand, the group now favors sicker patients over soccer moms. GHA physicians say they now have more incentive to get preventive care to those with chronic diseases, although that may be because capitation never put GHA at risk for hospital costs.

Print editions of the January/February issue on "U.S. Hospitals: Mission Vs. Market" may be ordered for $35 each from Health Affairs' Customer Service at 301-347-3900 or online athttp://www.healthaffairs.org/1330_issue.php


ABOUT HEALTH AFFAIRS:

Health Affairs, published by Project HOPE, is the leading journal of health policy. The peer-reviewed journal appears bimonthly in print with additional online-only papers published weekly as Health Affairs Web Exclusives at www.healthaffairs.org. The full text of each Health Affairs Web Exclusive is available free of charge to all Web site visitors for a two-week period following posting, after which it switches to pay-per-view for nonsubscribers. The abstracts of all articles are free in perpetuity. Web Exclusives are supported in part by a grant from the Commonwealth Fund.

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View Article  RFID production to increase 25-fold by 2010
According to a new report RFID production is to increase 25-fold in four years, buoyed on by the scramble by pharmaceutical manufacturers to comply with the new RFID Certification program, which aims to synchronise the industry’s transition to RFID technology.

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In-PharmaTechnologist.com
View Article  Africa's Polio Efforts Aiding Bird Flu Fight
Africa's response to the first appearance of H5N1 bird flu on the continent may be aided by its fight against an entirely unrelated infection -- polio.

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WashingtonPost.com
View Article  Bird Flu Spreads to European Union for First Time
The bird flu virus has been found in wild birds in Italy and Greece, the first time it has been detected in the European Union.

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NYTimes.com
View Article  Researchers Race to Boost Supply of Bird Flu Vaccine
Additives Studied as Way to Help Fight Potential Pandemic

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WashingtonPost.com
View Article  Spread of Bird Flu Boosts Pandemic Chances
UNITED NATIONS (AP) -- The spread of bird flu from Asia to eastern Europe and now west Africa has increased the chance the virus will mutate and set off a pandemic, the U.N. bird flu chief said.

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NYTimes.com
View Article  The second wave in kinase cancer drugs
Cancer drugs targeting signaling pathways have been hampered by problems of efficacy and tumor resistance. Will the next generation of kinase inhibitors fare better than the first? Ken Garber investigates.

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Nature Biotechnology
View Article  GEN's Sticky Ends Online For February 8, 2006
ACT Launches Research Laboratory in California
Support for stem cell research drives company's move. Full Story

Amgen Expands Manufacturing Capability in Puerto Rico
Company cites rising demand for products as key in decision to expand. Full Story

Cambrex BioScience Walkersville to Purchase Cutanogen
Acquisition enhances wound-care franchise. Full Story

CureVac Raises 22 Million €
Investment from SAP founder will push its main product through Phase II trial. Full Story

GlycoGenesys Reports Chapter 11 Filing, Reduction in Work Force, and Management Changes
Company reduces expenses to pursue strategic alternatives while maintaining multiple myeloma trial. Full Story

Sigma-Aldrich Launches Lentiviral shRNA Gene Family Set
Target set can be used to create a stable knockdown in mammalian cells. Full Story

Vaccine Protects Children from Rotavirus Infection
An estimated 440,000-600,000 childhood deaths worldwide each year attributed to the infection. Full Story

www.genengnews.com
View Article  Rapid Microbiological Methods for a New Generation
These are exciting times, as 19th-century microbiological methods make way for rapid detection, quantification and characterization technologies.

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PharmaManufacturing.com
View Article  The Human Genome Project +5
The five years since the draft of the human genome was published have been productive but bumpy. What will the next five be like?

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The-Scientist.com